Хроноструктура биоритмов сердца как маркер ранней кардиотоксичности противоопухолевых лекарственных препаратов

Chronostructure of cardio-vascular biorrhytms as a marker of early cardiotoxicity at the anti-cancer chemotherapy

Use of modern highly effective anticancer chemotherapy has revealed necessity of diagnostics of the early cardiotoxic side-effects. Cardiotoxicity often entails sharp or chronic progressing cardiomyopathy which leads to disability of patients, off-scheduled hospitalisation and additional drug treatment. As result at 10% of patients carrying out effective chemotherapy becomes not possible.