The article aims to present and characterize the leading and most popular digital technologies for supporting the educational process in higher education and to show the opportunities and prospective applications arising in the context of Industry 4.0, whose inextricable element is its relationship with technological progress. The paper outlines the current state of higher education didactics in light of advancements in information technology. It describes the principal aspects of teaching with a reliance on educational portals, mobile learning, and Web 2.0. Given the incremental advancement of scientific and technological progress, the authors examine the influence of Industry 4.0 technologies on higher education and the associated prospects of Education 4.0 in higher education. The study concludes that newly emerging professions require teaching new competencies, and introducing Industry 4.0 technologies in higher education necessitates profound changes, which becomes a challenge for the Russian education system.