A genetically encoded Mango II-based system with increased brightness and selectivity for imaging RNAs in live cells

A new biotin-free fluorogenic dye with improved selectivity for Mango II over endogenous nucleic acid structures was developed. It shows increased brightness when complexed with Mango-labeled RNA within live cells compared to the known analogue.

Авторы
Svetlova J.I. 1 , Bychenko O.S. 2 , Slushko G.K. 2, 3 , Skvortsova Y.V. 2 , Belyaev E.S. 4 , Kamzeeva P.N. 2 , Khodarovich Y.M. 2, 5 , Pakhomov A.A. 2 , Azhikina T.L. 2 , Varizhuk A.M. 1 , Aralov A.V. 1, 2, 5
Journal
Organic & Biomolecular Chemistry
Издательство
Royal Society of Chemistry
Язык
English
Статус
Published
Год
2025
Организации
  • 1 Lopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency
  • 2 Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of Russian Academy of Sciences
  • 3 D. Mendeleev University of Chemical Technology of Russia
  • 4 Frumkin Institute of Physical Chemistry and Electrochemistry of Russian Academy of Sciences
  • 5 RUDN University
Цитировать
ГОСТ MLA RIS BibTex
Поделиться

Другие записи

АКТУАЛЬНЫЕ ПРОБЛЕМЫ МЕЖДУНАРОДНЫХ ОТНОШЕНИЙ И ВНЕШНЕЙ ПОЛИТИКИ В ХХI ВЕКЕ

Monograph
Avatkov V.A., Apanovich M.Yu., Borzova A.Yu., Bordachev T.V., Vinokurov V.I., Volokhov V.I., Vorobev S.V., Gumensky A.V., Иванченко В.С., Kashirina T.V., Матвеев О.В., Okunev I.Yu., Popleteeva G.A., Sapronova M.A., Свешникова Ю.В., Fenenko A.V., Feofanov K.A., Tsvetov P.Yu., Shkolyarskaya T.I., Shtol V.V. ...
Общество с ограниченной ответственностью Издательско-торговая корпорация "Дашков и К". 2018. 411 с.