Arylation of 2,5-dimethyl-4-phenylpyridine

The α position of the pyridine ring is arylated by reaction of 2,5-dimethyl-4-phenylpyridine with phenyllithium and p-tolyllithium. Destructive oxidation of the diaryl-substituted pyridines primarily affects the pyridine ring. © 1973 Consultants Bureau.