The IMDAV reaction between 3-(isoxazol-3-yl)allylamines and maleic anhydrides: an unusual approach to pyrrolo[3,4-c]pyridine derivatives, possessing anti-inflammatory activity

A concise preparative IMDAV strategy for the synthesis of pyrrolo[3,4-c]pyridines, which exhibit anti-inflammatory activity, starting from readily available materials was proposed.

Авторы
Zaytsev V.P. 1 , Simakova D.N. 1 , Maslova V.S. 1 , Ilyushenkova V.V. 2 , Novikov R.A. 3 , Grigoriev M.S. 4 , Danilov R.D. 5 , Litvinov Roman 5, 6 , Kolesnik I.A. 7 , Potkin V.I. 7 , Zubkov F.I. 1
Journal
Organic & Biomolecular Chemistry
Издательство
Royal Society of Chemistry
Номер выпуска
16
Язык
English
Страницы
3925-3936
Статус
Published
Том
23
Год
2025
Организации
  • 1 RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
  • 2 Zelinsky Institute of Organic Chemistry of RAS, 47 Leninsky Prospect, Moscow, 119991, Russian Federation
  • 3 V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov St., Moscow, 119991, Russian Federation
  • 4 Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninsky pr. 31, bld. 4, Moscow, 119071, Russian Federation
  • 5 Volgograd State Medical University 1, Pl. Pavshikh Bortsov Square, Volgograd, 400131, Russian Federation
  • 6 LLC “InnoVVita”, Office 401, Room 2, 6 Komsomolskaya St., Volgograd, 400066, Russian Federation
  • 7 Institute of Physical Organic Chemistry of National Academy of Sciences of Belarus, 13 Surganov str., 220072 Minsk, Belarus
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