Expansive soil spatial variability plays a key role in the over- and under-application of fertilizers, contributing to environmental pollution. Assess soil variability and delineate it into management zones to adopt site-specific nutrient management for balanced fertilization and sustainable agriculture. To assess spatial variability by geostatistical methods and delineate and evaluate nutrient management zones for site-specific nutrient management and variable rate fertilizer application using fuzzy c-means clustering. Overall, 200 soil samples (0–15 cm depth) with geographical coordinates were collected with a grid size of 14.2 m × 14.2 m from a 4-ha maize cultivated 4-ha of Mahagoan village of Bhainsa Mandal, Nirmal district, Telangana, India. The collected samples were tested with different reagents to determine the soil reaction and available nutrient status. Soil spatial variability was assessed by the geostatistical method, and delineation of nutrient management zones was carried out by integrating principal component analysis and fuzzy c-means clustering. Geostatistical analysis revealed spherical (pH, electrical conductivity, organic carbon, available sulfur, and available Zn) and Gaussian (available nitrogen, available P