Renander–Müller disease: current state of the problem

This scientific data review addresses the issues of diagnosis and treatment of avascular necrosis of the sesamoid bones, also known as Renander–Müller disease. This condition is relatively rare and predominantly affects physically active young individuals. The combination of these two factors contributes to diagnostic challenges, persistent functional impairment, and a high rate of disability. No publications on this condition were found in Russian. The scientific data search was conducted using the PubMed, Medline, Scopus, Google Scholar, and eLIBRARY databases. A total of 47 publications were included in the review. The search was performed using the following keywords, their derivatives, and combinations in the titles and abstracts: avascular necrosis of the sesamoid, sesamoid AVN, hallucial sesamoid disorders, Renander–Müller disease, osteonecrosis, sesamoidectomy, and sesamoid. The initial screening for inclusion criteria was conducted using the titles and abstracts, followed by full-text analysis of the selected articles. Sources without accessible full-text versions were excluded from the analysis. © 2025 Elsevier B.V., All rights reserved.