Results of Conservative Therapy of Baker Grade II-III Capsular Contracture Treatment with Botulinum Toxin Type A; Результаты консервативной терапии капсулярной контрактуры II-III степени по Baker с помощью ботулинического токсина типа А

Introduction. Capsular contracture (CC) is the most common and clinically significant complication in both aesthetic and reconstructive surgery for breast cancer (BC), requiring reoperation in most cases. Aim. To identify indications for the prevention and conservative treatment of CC. Materials and Methods. The study included 25 patients with Baker grade II-III CC following reconstructive plastic surgery for combined/complex treatment of BC who underwent conservative treatment with botulinum toxin type A (BTA). Results. Patients with a mean age of 48.3 ± 0.6 years were included in the study. Prior to the introduction of botulinum toxin type A, the capsule thickness was measured by ultrasound (US) and averaged 1.94 ± 0.05 mm. The maximum number of repeated injections was 3 in 6 months. Patients who received BTA for stage II-III CC showed a positive effect in terms of reduced pain and decreased deformation of the reconstructed mammary gland. After 2 months, the therapeutic effect was maintained and the mean capsule thickness was 1.51 ± 0.05 mm. Conclusion. BTA injections may become a potential new method in the treatment of CC after reconstructive plastic surgery for BC. © 2025 Elsevier B.V., All rights reserved.