INTRODUCTION. The temporomandibular joint (TMJ) plays a crucial role in mastication, speech, and maintaining overall postural balance. Dysfunction in TMJ biomechanics can lead to local pain, functional limitations, and postural disturbances. Despite advances in digital technologies and the integration of osteopathy into dental practice, there remains a lack of accessible and validated tools for dynamic TMJ monitoring. AIM. To develop and validate a method for quantitative assessment of mandibular biomechanics using craniometric measurements and digital technologies. MATERIALS AND METHODS. Ninety patients aged 19 to 61 years with TMJ dysfunction and extra-occlusal disorders were enrolled. Participants were divided into a main group, which received both dental and osteopathic treatment, and a control group, which received dental treatment only. Standardized digital imaging was performed pre-and post-treatment. Mandibular deviation was assessed by measuring the angle and perpendicular distance from the sagittal plane using a mobile application. Statistical analysis was performed using IBM SPSS Statistics version 26.0, with significance set at p < 0.05. RESULTS. A statistically significant reduction in mandibular deviation was observed in both groups (p < 0.05), with the main group showing greater improvements. The findings support the effectiveness of combining osteopathic correction with dental therapy in restoring mandibular biomechanics. CONCLUSIONS. The proposed method provides an objective and efficient tool for assessing the outcomes of dental and osteopathic interventions in patients with TMJ dysfunction and offers potential for early detection of biomechanical impairments. © 2025 Elsevier B.V., All rights reserved.