Quality of life in pediatric patients after completion of antitumor therapy for malignant neoplasms of the kidneys; Качество жизни пациентов детского возраста после завершения противоопухолевой терапии злокачественных новообразований почек

Introduction. The number of children and adolescents cured of malignant neoplasms (MN) is growing worldwide. An important task of modern pediatric oncology is to maintain quality of life (QOL) after the end of intensive antitumor therapy. The aim of the study was to study the QOL of patients with MN of the kidneys at the stages of rehabilitation. Results and discussion. Patients and parents filled out the relevant forms of the PedsQuality of Life Inventory Generic Core Scales (PedsQL) general quality of Life assessment questionnaire. A comparative analysis of the patients' QOL was performed depending on the age of the patients at the time of the disease, the duration of remission, and the type of renal insufficiency. Conclusions. The QOL assessment technique confirms the effectiveness of rehabilitation technologies in patients with renal insufficiency; after rehabilitation treatment, regardless of the type of tumor, an increase in QOL parameters is noted. The QOL estimates made by parents of patients with Wilms tumor (WT) are lower than those in pediatric forms of PedsQL, regardless of the volume of the tumor lesion and the age of the patients. The lowest QOL is observed in WT patients in the first 3 years after the end of antitumor therapy, which should motivate specialists and parents to start rehabilitation as early as possible. On 10-12 years of follow-up, QOL indicators decrease, probably due to the cumulative effect of other medical and social risk factors, preventing the achievement of the population level of QOL. © 2025 Elsevier B.V., All rights reserved.