The impact of abdominal obesity correction in mature women on the structural and functional parameters of the myocardium and lipid metabolism parameters

Obesity is a serious medical problem. Obesity prevention is a social and biomedical task. Objective. To analyze the effect of the program for the correction of grade I abdominal obesity in middle-aged premenopausal women on the structural and functional changes in the myocardium and the lipid composition of peripheral blood. Materials and methods. Anthropometric indicators, echocardiography examination, and blood lipid composition in females diagnosed with grade I obesity of the control (n=25) and main groups (n=25) at the age of 42±1.5 years were analyzed. The data were obtained during the patient’s first visit and after 6 months of follow-up to track changes in body weight due to aerobic exercise. Results. The integrated approach to reducing body weight and normalizing blood pressure using aerobic exercise showed positive changes: a decrease in the end-diastolic size of the left ventricle by 4.8%, the left ventricular mass index by 5.4%, an increase in the ejection fraction by 7.8%, and the normalization of the blood lipid profile. Conclusions. Changes in anthropometric parameters, disturbances in the blood lipid profile, and abnormal heart diastolic function are observed in obese women. Rehabilitation and wellness programs play a crucial role in organizing and implementing the obesity prevention and treatment system. A significant improvement in the lipid profile was observed at 6 months in women with grade I obesity who received a comprehensive program for treating abdominal obesity. © 2025 Elsevier B.V., All rights reserved.