Features of clinical and laboratory diagnostics of scalp mycosis; Особенности клинической и лабораторной диагностики микоза волосистой части головы

Introduction. Mycosis of the scalp (Tinea capitis) is one of the most common infections localized on the scalp and occurs mainly in children. The frequency of purulent inflammatory type (Kerion celsii) is about 15% of all cases of of scalp mycosis. The causative agents are zoophilic dermatophyte fungi that cause skin mycoses in cattle, donkeys, dogs, goats, sheep and horses. Zoonotic infection Trichophyton verrucosum is reported ubiquitously, more frequently in Asia and the Middle East. Human infection occurs in rural areas where close contact with animals is more likely. The urgency of the problem is associated with the increasing number of cases of severe scalp mycosis caused by T. verrucosum. Aim. Analyse clinical and laboratory features of T. verrucosum infection. Results. The article describes two cases of mycosis of the scalp caused by T. verrucosum. Both patients received complex treatment in the inpatient department of the Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology. Effective treatment was delayed due to incorrect clinical and laboratory diagnosis of the disease. After hospitalization in the pediatric dermatovenereology department, both patients quickly responded to treatment with oral antifungals. No growth of T. verrucosum culture was obtained during laboratory diagnostics of pathological material. Direct microscopy revealed an ectothrix-like arrangement of spores. Conclusions. Due to active migration and the popularity of tourism, dermatovenerologists in their daily practice must be prepared for an increase in infectious diseases. A properly collected anamnesis allowed specialists to establish the correct diagnosis of scalp mycosis caused by a zoophilic dermatophyte. In the given clinical examples, when the bacteriological method did not give a result, direct microscopy allowed to confirm the clinical diagnosis, identify the etiologic agent (T. verrucosum) and optimize the tactics of systemic and topical therapy. © 2025 Elsevier B.V., All rights reserved.