PULSED WIDE-SPECTRAL PHOTOTHERAPY OF SOFT TISSUE GUNSHOT WOUNDS; ИМПУЛЬСНАЯ ШИРОКОСПЕКТРАЛЬНАЯ ФОТОТЕРАПИЯ ОГНЕСТРЕЛЬНЫХ РАН МЯГКИХ ТКАНЕЙ

A new method has been proposed for the treatment of gunshot wounds complicated by nosocomial microflora. The method is based on the treatment of wounds with high-intensity pulsed optical radiation of a continuous spectrum in the wavelength range from 200 to 1100 nm. A pulsed xenon lamp is used as a radiation source. The effect of high-intensity pulsed wide-spectrum optical radiation and low-intensity continuous UV radiation with a maximum at a wavelength of 272 nm and a half-width of the spectrum of 12 nm on the course of the wound process in a gunshot injury was compared. It has been shown that the effect of such radiation on tissues with signs of purulent-inflammatory process provides an antibacterial effect and stimulates tissue regeneration. At the same time, high-intensity wide-spectral optical radiation has a more pronounced anti-inflammatory effect and contributes to the earlier development of tissue regeneration compared with low-intensity narrow-spectrum UV radiation. However, the use of high-intensity optical radiation requires an individual dosage for each phase of the wound process. © 2025 Elsevier B.V., All rights reserved.

Авторы
Bagrov Valery V. 1 , Bobin Alexander Nikolaevich 2 , Bobylev V.A. 2 , Volodin Lev Y. 1 , Davydov D.V. 2, 3 , Kamrukov Alexander S. 1 , Kondratiev Andrey V. 1 , Nesterova M.V. 2 , Pecherskaya M.S. 2 , Fateev A.V. 2 , Shchedrina M.A. 2 , Esaulenko Nikolai B. 2
Издательство
Некоммерческое партнерство развития отечественной фотодинамической терапии и фотодиагностики "Национальная фотодинамическая ассоциация"
Номер выпуска
1
Язык
English
Страницы
20-28
Статус
Published
Том
14
Год
2025
Организации
  • 1 Bauman Moscow State Technical University, Moscow, Russian Federation
  • 2 Main Military Clinical Hospital named after Academician N. N. Burdenko of the Ministry of Defense of the Russian Federation, Moscow, Russian Federation
  • 3 RUDN University, Moscow, Russian Federation
Ключевые слова
antibacterial effect; gunshot wound; optical radiation; pulsed wide-spectrum phototherapy; tissue regeneration
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