Общество с ограниченной ответственностью Издательско-торговая корпорация "Дашков и К". 2018. 411 с.
Total synthesis of the taraxacine A natural product via Ag(I)-catalysed imidate-alkyne cyclization
A domino approach towards β-carboline natural product taraxacine A and its analogues was developed. The main step relies on a silver(I) and base co-catalysed imidate-alkyne cyclization. The reaction tolerates primary and secondary alcohols, and various substitutions in the indole are possible. © 2025 Elsevier B.V., All rights reserved.
Авторы
Zalte Rajesh R. 1 , Festa Alexey A. 1 , Demidov Sergei A. 1 , Awuku Samuel O. 1 , Golubenkova Alexandra S. 1 , Mironov Yuri Y.U. 1 , Golantsov Nikita E. 1 , Storozhenko Olga A. 1 , Novikov Anton Petrovich 2 , Voskressensky Leonid G. 1
Издательство
Royal Society of Chemistry
Номер выпуска
6
Язык
English
Страницы
1386-1393
Статус
Published
Ссылка
Том
23
Год
2024
Организации
- 1 Department of Organic Chemistry, RUDN University, Moscow, Russian Federation
- 2 A.N. Frumkin Institute of Physical Chemistry and Electrochemistry of the Russian Academy of Sciences, Moscow, Russian Federation
Ключевые слова
Catalysis; Cyclizations; Imidates; Natural products; Primary alcohols; Secondary alcohols; Silvers (i); Total synthesis; β-carboline; Cyclization; alcohol; alcohol derivative; alkyne; beta carboline; natural product; silver; article; drug analysis; drug development
Поделиться
Другие записи
Регионарная анестезия и лечение острой боли. Том 18. 2024. С. 356-372