The short route to chalcogenurea-substituted 3a,6-epoxyisoindoles via an intramolecular Diels–Alder furan (IMDAF) reaction. Antibacterial and antifungal activity

A concise preparative IMDAF strategy for the synthesis of chalcogenurea-substituted 3a,6-epoxyisoindoles, which display antifungal and antibacterial activity, starting from readily available materials was proposed.

Авторы
Mertsalov D.F. 1 , Shchevnikov D.M. 1 , Lovtsevich L.V. 1 , Novikov R.A. 2 , Khrustalev V.N. 1, 3 , Grigoriev M.S. 4 , Romanycheva A.A. 5 , Shetnev A.A. 6 , Bychkova O.P. 7 , Trenin A.S. 7 , Zaytsev V.P. 1
Journal
New Journal of Chemistry
Издательство
Royal Society of Chemistry
Номер выпуска
29
Язык
English
Страницы
12947-12959
Статус
Published
Том
48
Год
2024
Организации
  • 1 RUDN University, 6 Miklukho-Maklaya St., Moscow 117198, Russian Federation
  • 2 V. A. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov St., Moscow, 119991, Russian Federation
  • 3 Zelinsky Institute of Organic Chemistry of RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation
  • 4 Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninsky pr. 31, bld. 4, 119071, Moscow, Russian Federation
  • 5 Pharmaceutical Technology Transfer Center, Yaroslavl State Pedagogical University Named After K. D. Ushinsky, 108/1 Republican St., 150000, Yaroslavl, Russian Federation
  • 6 Moscow Institute of Physics and Technology 1 “A” Kerchenskaya St., Moscow, 117303, Russian Federation
  • 7 Gause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russian Federation
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