Crystal structure and Hirshfeld surface analysis of (22RS,23SR,25RS,26SR)-23,25,5-trimethyl-21-(2,2,2-trifluoroacetyl)-5-aza-2(2,6)-piperidina-1,3(2,5)-difuranacyclohexaphan-24-one

The title compound, C20H21F3N2O4, features a main twelve-membered difuryl ring with which the furan rings make dihedral angles of 76.14 (5) and 33.81 (5)̊. The dihedral angle between the furan rings is 42.55 (7)̊. The six-membered nitrogen heterocycle has a twist-boat conformation. In the crystal, pairs of molecules are connected by intermolecular C—H. . .O interactions, generating an R22(14) ring motif. These pairs of molecules form zigzag chains along the a-axis direction by means of C—H. . .F interactions. Furthermore, C—H. . .π and C–F. . .π interactions link the molecules into chains along the b-axis direction, forming sheets parallel to the (001) plane. These sheets are also connected by van der Waals interactions. © 2023 International Union of Crystallography. All rights reserved.