Dystrophic changes in the teeth and their surrounding tissues in destructive forms of apical periodontitis

Aim. With the help of pathomorphological studies, to study dystrophic changes that occur in teeth with destructive forms of periodontitis in the acute stage and in the tissues surrounding them. Materials and methods. For morphological study, biopsies of 48 teeth and periapical foci of infection of destructive forms of apical periodontitis in the acute stage were used. The material processed according to generally accepted methods was studied using an Olympus BX-40 light microscope. Results. Dystrophic changes were observed in 9 out of 48 studied teeth, which amounted to 18.75 %. Various manifestations of dystrophy testified to pathomorphological changes in tissues during the chronic course of the disease. Conclusions. Exacerbation of the inflammatory process in destructive periodontitis is accompanied by an autoimmune response of the body. Calcifications indicate changes in tissues. Dystrophy leads to total necrosis of pulp and periodontal tissues. Tissue granulomas with signs of dystrophy, chronic inflammatory process. Accumulation in the tissues of dental granulomas during the period of exacerbation of GAG is uneven, mostly of low and moderate intensity with a predominance of non-sulfated compounds. The body on its own is not able to cope with a long-standing inflammatory process. © 2023, Endo Press LLC. All rights reserved.