The article examines the main provisions of the concept of regional sectoral development in modern trends of sustainable development and digitalization, which is aimed at ensuring the competitiveness of a specific territory, self-sufficiency of specific sectors of the economy. Undoubtedly, the vectors of the digital economy and sustainable development have a direct impact on technological and innovative processes, as well as the need to transition to a new technological order in each region of Russia. The region, being a territorial natural and social complex, concentrates natural, social and economic resources. The development of regional industries takes place in the system of subject-object relations based on the theory and methodology of economic science. © 2024 The Authors, published by EDP Sciences.