Metastatic Merkel carcinoma complicated by transverse myelitis during immuno-oncological therapy; [Метастатическая карцинома Меркеля, осложненная на фоне иммуноонкологической терапии поперечным миелитом]

Objective. To present a unique clinical case of metastatic lesions of the perirenal space, ureter and bladder in Merkel's carcinoma with the development of transverse myelitis against the background of immuno-oncological therapy. Matherial and methods. The modern states of issue in diagnose and treatment of metastatic Merkel's carcinoma within multidisciplinary approach based on the medical documentation and radiological examinations (CT, MRI) was analysed in this article. Results. The unique clinical case of metastatic Merkel's carcinoma complicated by transverse myelitis during immuno-oncological therapy according to MSCT and MRI examinations report was demonstrated. Conclusion. Radiological examinations such as MSCT, MRI, ultrasound and PET/CT needed for detection, assess the incidence of tumor (metastasis and staging) and treatment efficiency control because of the rare occurrence and insufficient knowledge of Merkel's carcinoma. © 2022 Infectious Diseases: News, Opinions, Training.

Авторы
Karpova A.A. , Nikitin P.A. , Znamenskiy I.A. , Nudnov N.V. , Vorobeva V.O. , Ardyukova N.E.
Номер выпуска
4
Язык
Русский
Страницы
32-43
Статус
Опубликовано
Том
26
Год
2022
Организации
  • 1 Central Clinical Hospital, the Russian Academy of Sciences, Lithuanian Boulevard, 1A, Moscow, 117593, Russian Federation
  • 2 Pirogov Russian National Research Medical University of the Ministry of Health of Russia, Ostrivityanova str., 1, Moscow, 117997, Russian Federation
  • 3 Russian Scientific Center of Roentgenoradiology, the Ministry of Healthcare of the Russian Federation, 86, Profsoyuznaya str., Moscow, 117997, Russian Federation
  • 4 Russian Medical Academy of Continuous Professional Education, Barrikadnaya str., 2/1, bld. 1, Moscow, 125993, Russian Federation
  • 5 People’s Friendship University of Russia, 6, Miklukho-Maklaya str., Moscow, 117198, Russian Federation
Ключевые слова
CT; immune-mediated myelitis; Merkel carcinoma; MRI; PD-1; perirenal space
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