Risk Factors Impact for the Formation of Primary Organic Mental Disorders Complicated by Alcohol Dependence in Middle-aged and Aged; [Факторы риска формирования первичных органических психических расстройств, осложненных алкогольной зависимостью в среднем и пожилом возрасте]

Background: the economic and political transformations taking place today reduce adaptation, cause a variety of psychological reactions and mental disorders, including organic psychic disorders (OPD). Elderly people are especially susceptible to these reforms and the emergence of various disorders. Some persons resort to drinking alcohol to alleviate various psychological disorders. In connection with the above, the study of the problem of the formation of organic mental disorders and alcoholism is very justified. The aim was: to study risk factors (RF) influencing the development of primary organic mental disorders complicated by alcohol dependence in middle-aged and elderly patients. Patients and Methods: 83 male patients aged 67.5 ± 7.2 years with primary organic psychic disorders (POPD) complicated by middle stage alcohol dependence (AD) were included. Taking into account the age parameter of disease manifestation, patients were divided into 2 groups: the 1st group included 49 people (59%), the 2nd group included 34 (41%), in whom symptoms of POPD appeared at 38.2 ± 2.0 and 46.5 ± 2.2 years, respectively, and AD formed at 53.8 ± 1.2 years and 66.8 ± 0.9 years, respectively. Methods used: survey, clinical follow-up, statistical. Results: as a result of the study using the “Anamnestic Card”, etiological RF for the formation of POPD were identified — internal biophysiological (nonspecific) risk factors (antenatal, intranatal, postnatal, closed TBI, chronic somatic diseases). Conclusion: the formation of POPD is influenced by past closed TBI and other exogenous-organic harms, combinations of RF, hereditary burden of alcoholism in the 1st line of kinship, and childhood chronic somatic diseases. The age of formation of POPD is determined by the quantity, and possibly quality, of childhood somatic chronic diseases and combinations of RF, as well as the age of closed TBI. The progression of alcoholism is combined with the age of onset of TBI, hereditary burden of alcoholism in the 1st line of kinship, the number and age of subsequent somatic pathology. © Кардашян Р.А. и др., 2024