Synthesis of chromeno[2′,3′:4,5]imidazo[2,1-a]isoquinolines via a novel domino reaction of isoquinoline-derived immonium salts. Scope and limitations

A one-pot protocol towards chromeno[2′,2′:4,5]imidazo[2,1-a] isoquinoline derivatives via a domino reaction of isoquinoline-derived immonium salts and α-hydroxy aromatic aldehydes is elaborated. The scope and limitations of this reaction is discussed. © 2012 Elsevier Ltd. All rights reserved.