A novel synthesis of pyrrolo[1,2-d][1,4]diazocines from tetrahydropyrrolo[1,2-a] pyrazines using activated alkynes in pyrazine ring expansion

A novel and efficient one-pot synthesis of pyrrolo[1,2-d][1,4]diazocines based on tandem transformation of tetrahydropyrazine ring was elaborated. © 2010 Elsevier Ltd.