Spontaneous Regression of a Lumbar Juxtafacet Cyst: A Case Report and Literature Review

This report examines the rare phenomenon of spontaneous regression of a lumbar perineural cyst. Lumbar perineural cysts, typically associated with nerve root compression, are generally managed surgically. However, instances of nonsurgical resolution have been documented. A 54-year-old male presented with lower back and left leg pain, with magnetic resonance imaging (MRI) revealing a perineural cyst at the left L4-L5 level. Choosing conservative management, the patient experienced an unexpected and swift regression of the cyst, confirmed by follow-up MRI. This case illustrates the potential for conservative management in lumbar perineural cysts and underscores the importance of individualized patient care. It challenges the traditional surgical preference and advocates for flexible, patient-centered treatment approaches in spinal pathology. © 2025 Elsevier B.V., All rights reserved.