Background: Antiaging research today uses AI, IoT, and blockchain tech to change the medical and financial sectors plus construction services. The integration of fluoride-related initiatives with modern technology like water fluoridation and dental items presents ways to make better use of fluoride while creating less damage to our planet. These advanced technologies have not been fully tested to see how they could both run fluoride health programs better and make them more sustainable. This research examines the benefits of implementing both advanced technical systems and financial data tools to enhance fluoride-based projects and their sustainability benefits Aim: Our research tests how AI, IoT, and blockchain technology affects financial data analytics to reach better fluoride-based project results. The research uses multiple advanced technologies to boost the effective use of resources while making fluoride health initiatives sustainable. Methodology: Through the use of Smart PLS tool in SEM this research analyzes how advanced technology elements work with financial data analysis methods to boost environmental sustainability and maximize fluoride's potential. Participating stakeholders sent back surveys with responses as we gathered data from project managers, engineers and data analysts working on fluoride-based projects. Different statistical tests helped measure the identified constructs using established scales while proving the model's reliability for analysis. Implications: The research shows that adding advanced technology to fluoride projects boosts transparency and operations while making projects greener. Financial data analysis helps allocate resources better to make fluoride-based projects more sustainable. Health professionals and officials should embrace modern technological tools to build a sustainable future for the fluoride health industry. Conclusion: Fluoride-based health projects gain important advantages through AI, IoT, blockchain, and financial data analytics technology. These systems help projects work better with lower costs and less environmental damage. Our research demonstrates how digital transformation helps projects better use fluoride supplies to create more sustainable development results. Research teams should now assess how these technologies work over extended periods while adding social and political environment data to study results. © 2025 Elsevier B.V., All rights reserved.