Sequential three-component reaction of homophthalonitrile, salicylaldehydes and nitromethane

An effective preparative multi-component synthesis of 12-nitromethyl-12H-chromeno[2,3-c]isoquinolin-5-amines comprised sequential reactions of salicylaldehydes with homophthalonitrile and then with nitromethane under MW irradiation. © 2017