ctDNA transiting into urine is ultrashort and facilitates noninvasive liquid biopsy of HPV+ oropharyngeal cancer

BACKGROUND. Transrenal cell-free tumor DNA (TR-ctDNA), which transits from the bloodstream into urine, has the potential to enable noninvasive cancer detection for a wide variety of nonurologic cancer types.

Авторы
Bhambhani Chandan 1 , Kang Qing 1 , Hovelson D.H. 2, 3 , Sandford Erin 1 , Olesnavich Mary 1 , Dermody S.M. 4 , Wolfgang Jenny 1 , Tuck K.L. 1 , Brummel Collin 4 , Bhangale A.D. 4 , He Kuang 1 , Gutierrez M.G. 5 , Lindstrom R.H. 1 , Liu Chia-Jen 3, 6 , Tuck Melissa 1 , Kandarpa Malathi 1 , Mierzwa Michelle 7, 8 , Casper Keith 4, 8 , Prince M.E. 4, 8 , Krauss J.C. 1 , Talpaz Moshe 1 , Henry N.L. 1, 8 , Giraldez M.D. 1, 9 , Ramnath Nithya 1 , Tomlins S.A. 3, 6, 10 , Swiecicki P.L. 1, 8 , Brenner J.C. 4, 8, 11 , Tewari Muneesh 1, 8, 12, 13
Журнал
Номер выпуска
6
Язык
Английский
Статус
Опубликовано
Том
9
Год
2024
Организации
  • 1 Department of Internal Medicine, Division of Hematology/Oncology,
  • 2 Department of Computational Medicine & Bioinformatics,
  • 3 Michigan Center for Translational Pathology,
  • 4 Department of Otolaryngology,
  • 5 Department of Internal Medicine,
  • 6 Department of Pathology,
  • 7 Department of Radiation Oncology, and
  • 8 Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.
  • 9 Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío, Consejo Superior de Investigaciones Científicas, University of Seville, Seville, Spain.
  • 10 Department of Urology,
  • 11 Department of Pharmacology,
  • 12 Center for Computational Biology and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.
  • 13 Department of Biomedical Engineering, and
Цитировать
Поделиться

Другие записи

Аватков В.А., Апанович М.Ю., Борзова А.Ю., Бордачев Т.В., Винокуров В.И., Волохов В.И., Воробьев С.В., Гуменский А.В., Иванченко В.С., Каширина Т.В., Матвеев О.В., Окунев И.Ю., Поплетеева Г.А., Сапронова М.А., Свешникова Ю.В., Фененко А.В., Феофанов К.А., Цветов П.Ю., Школярская Т.И., Штоль В.В. ...
Общество с ограниченной ответственностью Издательско-торговая корпорация "Дашков и К". 2018. 411 с.