Pregnancy and childbirth with a pure form of gonadal dysgenesis, diagnosed at 16 years of age (Clinical observation)

The article presents a personal observation of the course of pregnancy and childbirth in a patient with a pure form of gonadal dysgen-esis (karyotype 46, XX). The diagnosis was made at the age of 16 during a comprehensive examination for primary amenorrhea, and hormone replacement therapy was performed. Pregnancy occurred after endometrial preparation with estrogens and progesto-gens on the background infusion of immunoglobulin, the result of the third attempt of IVF with donor egg (from the sister) and hus-band’s sperm, had a threatened miscarriage with bleeding on the background of carrier state of anti-β2-glycoprotein antibodies and a hypercoagulable state. At 36/37 weeks, she went into labor, and was delivered by cesarean section. © 2021, Media Sphera Publishing Group. All rights reserved.